Is “Upended” a Scrabble word?

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Yes
UPENDED
Valid in at least one Scrabble dictionary

Valid in these dictionaries

SOWPODS / CSW
Scrabble UK & International
Valid
TWL / NWL
Scrabble North America
Valid
Large English Dictionary
General English word list
Unavailable

Meaning of Upended

verb
  1. 1.To end up; to set on end.

  2. 2.To tip or turn over.

    When he upended the bottle of water over his sleeping sister, the lid popped off and surprised them both.

  3. 3.To destroy, invalidate, overthrow, or defeat.

    The scientific evidence upended the popular myth.