Is “Unsex” a Scrabble word?

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Yes
UNSEX
Valid in at least one Scrabble dictionary

Valid in these dictionaries

SOWPODS / CSW
Scrabble UK & International
Valid
TWL / NWL
Scrabble North America
Valid
Large English Dictionary
General English word list
Valid

Meaning of Unsex

verb
  1. 1.To deprive of sexual attributes or characteristics.

  2. 2.To sterilize (deprive of the ability to procreate); to castrate.