Is “Sprain” a Scrabble word?

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Yes
SPRAIN
Valid in at least one Scrabble dictionary

Valid in these dictionaries

SOWPODS / CSW
Scrabble UK & International
Valid
TWL / NWL
Scrabble North America
Valid
Large English Dictionary
General English word list
Unavailable

Meaning of Sprain

/spɹeɪn/

noun
  1. 1.The act or result of spraining; lameness caused by spraining

    a bad sprain of the wrist

Synonyms: wramp

verb
  1. 1.To weaken, as a joint, ligament, or muscle, by sudden and excessive exertion, as by wrenching; to overstrain, or stretch injuriously, but without luxation

    to sprain one's ankle