Is “Semes” a Scrabble word?

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Yes
SEMES
Valid in at least one Scrabble dictionary

Valid in these dictionaries

SOWPODS / CSW
Scrabble UK & International
Valid
TWL / NWL
Scrabble North America
Valid
Large English Dictionary
General English word list
Invalid

Meaning of Semes

/siːmz/

noun
  1. 1.A folded-back and stitched piece of fabric; especially, the stitching that joins two or more pieces of fabric.

  2. 2.A suture.

  3. 3.A thin stratum, especially of an economically viable material such as coal or mineral.

noun
  1. 1.Anything which serves for any purpose as a substitute for an object of which it is, in some sense, a representation or sign.

noun
  1. 1.(Japanese fiction) An active or dominant male character in a same-sex relationship; a top.