Is “Scruple” a Scrabble word?

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Yes
SCRUPLE
Valid in at least one Scrabble dictionary

Valid in these dictionaries

SOWPODS / CSW
Scrabble UK & International
Valid
TWL / NWL
Scrabble North America
Valid
Large English Dictionary
General English word list
Valid

Meaning of Scruple

noun
  1. 1.A weight of 1/288 of a pound, that is, twenty grains or one third of a dram, about 1.3 grams (symbol: ℈).

  2. 2.(by extension) A very small quantity; a particle.

  3. 3.A doubt or uncertainty concerning a matter of fact; intellectual perplexity.

Synonyms: s.ap.

verb
  1. 1.To hesitate or be reluctant to act due to considerations of conscience or expedience.

  2. 2.To excite scruples in; to cause to scruple.

  3. 3.To regard with suspicion; to question.