Is “Roofies” a Scrabble word?

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Yes
ROOFIES
Valid in at least one Scrabble dictionary

Valid in these dictionaries

SOWPODS / CSW
Scrabble UK & International
Valid
TWL / NWL
Scrabble North America
Valid
Large English Dictionary
General English word list
Unavailable

Meaning of Roofies

noun
  1. 1.(often plurale tantum) The date rape drug flunitrazepam.

  2. 2.(by extension) Any drug designed to make someone drowsy or disoriented.

Synonyms: roaches, rope