Is “Quire” a Scrabble word?

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Yes
QUIRE
Valid in at least one Scrabble dictionary

Valid in these dictionaries

SOWPODS / CSW
Scrabble UK & International
Valid
TWL / NWL
Scrabble North America
Valid
Large English Dictionary
General English word list
Unavailable

Meaning of Quire

/ˈkwaɪ.ə(ɹ)/

noun
  1. 1.One-twentieth of a ream of paper; a collection of twenty-four or twenty-five sheets of paper of the same size and quality, unfolded or having a single fold.

  2. 2.A set of leaves which are stitched together, originally a set of four pieces of paper (eight leaves, sixteen pages). This is most often a single signature (i.e. group of four), but may be several nested signatures.

  3. 3.A book, poem, or pamphlet.

verb
  1. 1.To prepare quires by stitching together leaves of paper.