Is “Pyxes” a Scrabble word?

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Yes
PYXES
Valid in at least one Scrabble dictionary

Valid in these dictionaries

SOWPODS / CSW
Scrabble UK & International
Valid
TWL / NWL
Scrabble North America
Valid
Large English Dictionary
General English word list
Invalid

Meaning of Pyxes

noun
  1. 1.A small, usually round container used to hold the consecrated bread of the Eucharist, especially used to bring communion to the sick, or others who are unable to attend Mass.

  2. 2.A box used in the British mint as a place of deposit for certain sample coins taken for a trial of the weight and fineness of metal before it is sent from the mint.

  3. 3.The box in which the compass is suspended; the binnacle.