Is “Loci” a Scrabble word?

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Yes
LOCI
Valid in at least one Scrabble dictionary

Valid in these dictionaries

SOWPODS / CSW
Scrabble UK & International
Valid
TWL / NWL
Scrabble North America
Valid
Large English Dictionary
General English word list
Invalid

Meaning of Loci

/ˈloʊsaɪ/

noun
  1. 1.A place or locality, especially a centre of activity or the scene of a crime.

    The cafeteria was the locus of activity.

  2. 2.The set of all points whose coordinates satisfy a given equation or condition.

    A circle is the locus of points from which the distance to the center is a given value, the radius.

  3. 3.A fixed position on a chromosome that may be occupied by one or more genes.