Is “Isthmi” a Scrabble word?

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Yes
ISTHMI
Valid in at least one Scrabble dictionary

Valid in these dictionaries

SOWPODS / CSW
Scrabble UK & International
Valid
TWL / NWL
Scrabble North America
Valid
Large English Dictionary
General English word list
Unavailable

Meaning of Isthmi

noun
  1. 1.A narrow strip of land, bordered on both sides by water, and connecting two larger landmasses.

  2. 2.Any such narrow part connecting two larger structures.

  3. 3.An edge in a graph whose deletion increases the number of connected components of the graph.