Is “Epigene” a Scrabble word?

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Yes
EPIGENE
Valid in at least one Scrabble dictionary

Valid in these dictionaries

SOWPODS / CSW
Scrabble UK & International
Valid
TWL / NWL
Scrabble North America
Valid
Large English Dictionary
General English word list
Invalid

Meaning of Epigene

adjective
  1. 1.Foreign; unusual; not natural to the substance in which it was found.

  2. 2.Of or pertaining to the region just below the surface of the earth.