Is “Dufuses” a Scrabble word?

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Yes
DUFUSES
Valid in at least one Scrabble dictionary

Valid in these dictionaries

SOWPODS / CSW
Scrabble UK & International
Valid
TWL / NWL
Scrabble North America
Valid
Large English Dictionary
General English word list
Invalid

Meaning of Dufuses

noun
  1. 1.A person with poor judgment and taste.

    Danny is such a doofus!

Synonyms: blockhead, boob, dolt, lowbrow, oaf