Is “Derail” a Scrabble word?

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Yes
DERAIL
Valid in at least one Scrabble dictionary

Valid in these dictionaries

SOWPODS / CSW
Scrabble UK & International
Valid
TWL / NWL
Scrabble North America
Valid
Large English Dictionary
General English word list
Unavailable

Meaning of Derail

/dəˈɹeɪl/

noun
  1. 1.A device placed on railway tracks causing a train to derail.

    The derail was placed deliberately so that the train would fall into the river.

  2. 2.An instance of diverting a conversation or debate from its original topic.

verb
  1. 1.To cause to come off the tracks.

    The train was destroyed when it was derailed by the penny.

  2. 2.To come off the tracks.

  3. 3.To deviate from the previous course or direction.

    The conversation derailed once James brought up politics.

Synonyms: unrail