Is “Defangs” a Scrabble word?

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Yes
DEFANGS
Valid in at least one Scrabble dictionary

Valid in these dictionaries

SOWPODS / CSW
Scrabble UK & International
Valid
TWL / NWL
Scrabble North America
Valid
Large English Dictionary
General English word list
Unavailable

Meaning of Defangs

verb
  1. 1.To remove the fangs from (something).

    The snake was defanged.

  2. 2.To render harmless.

Synonyms: declaw